What is the primary goal of performing cage changes on a predictable routine?

• A. To minimize stress.
• B. To maximize cleaning frequency.
• C. To increase handling time.
• D. To improve cage aesthetics.

Answer: (A)

Predictable cage changes reduce stress by turning a potentially disruptive event into a familiar, manageable routine. Mice are sensitive to environment changes and unpredictable handling; when the cleaning schedule is consistent, they can anticipate what will happen, which lowers fear and arousal during the process. This consistency also helps keep environmental conditions stable across changes, supporting comfort and overall welfare. The goal isn’t to clean more often, spend more time handling, or focus on appearance; it’s about reducing stress and maintaining a steady, humane housing routine.