When restraining a mouse for a procedure, which practice supports welfare?

• A. Apply full body pressure
• B. Use gentle handling and support the body
• C. Lift by the tail
• D. Restrain for extended periods without release

Answer: (B)

When restraining a mouse, the priority is reducing fear and physical stress, so the best approach is gentle handling with proper body support. This method keeps the animal calm, minimizes stress responses, and provides stable control without squeezing or causing injury. To do this, cradle the mouse close to your body and use one hand to support the chest and abdomen while the other supports the hindquarters, avoiding any lifting by the tail. Lifting by the tail can trigger strong fear, cause wriggling and possible tail injuries, and make restraint unstable. Holding with full body pressure or restricting breathing, or restraining for long periods without relief, increases distress and risk of harm. Gentle handling with good body support protects welfare and leads to safer, more reliable procedures.