Which statement best describes the function of an IACUC?

• A. Oversees the humane use of animals, ensures compliance, and reviews protocols
• B. Approves all research protocols without review
• C. Manages feeding schedules only
• D. Sets tuition for animal care courses

Answer: (A)

The function of an IACUC is to protect animal welfare in research by overseeing how animals are used, ensuring compliance with laws and guidelines, and reviewing the procedures researchers plan to use. Researchers submit protocols detailing species, numbers, procedures, anesthesia or analgesia plans, endpoints, and justifications. The committee evaluates these to minimize pain and distress, confirms that alternatives have been considered, and ensures numbers are justified. They also monitor ongoing work through inspections, post-approval monitoring, and regular reviews, and they can require modifications or suspend activities if welfare is at risk. This role goes beyond a one-time approval—it's ongoing oversight of the entire animal care and use program.